September 9 & 10
District 6 – September 9, 2022
| Altoona (Dist 6 AAAAAA 3-0-0) 38 Mifflin County (Dist 6 AAAAAA 2-1-0) 0 |
| Bald Eagle Area (Dist 6 AA 1-2-0) 48 Bellefonte (Dist 6 AAAA 0-3-0) 0 |
| Bellwood-Antis (Dist 6 AA 2-1-0) 40 Curwensville (Dist 9 A 2-1-0) 14 |
| Bishop Guilfoyle (Dist 6 AA 2-1-0) 55 Somerset (Dist 5 AAA 0-3-0) 7 |
| Cambria Heights (Dist 6 A 2-1-0) 35 River Valley (Dist 6 AA 0-3-0) 14 |
| Central Cambria (Dist 6 AA 1-2-0) 47 Johnstown (Dist 6 AAAA 0-3-0) 6 |
| Moshannon Valley (Dist 6 A 1-2-0) 29 Glendale (Dist 6 A 0-3-0) 14 |
| Mount Union (Dist 6 AA 2-1-0) 36 Tussey Mountain (Dist 5 A 1-2-0) 26 |
| Northern Cambria (Dist 6 A 3-0-0) 33 Purchase Line (Dist 6 A 1-2-0) 6 |
| Penn Cambria (Dist 6 AAA 3-0-0) 42 Central (Martinsburg) (Dist 6 AAA 1-2-0) 28 |
| Penns Manor (Dist 6 A 3-0-0) 26 Homer Center (Dist 6 A 2-1-0) 6 |
| Penns Valley (Dist 6 AA 3-0-0) 41 Huntingdon (Dist 6 AA 1-2-0) 14 |
| Portage (Dist 6 A 2-1-0) 42 Marion Center (Dist 6 A 0-3-0) 26 |
| Richland (Dist 6 AA 3-0-0) 38 Bishop McCort (Dist 6 A 1-2-0) 0 |
| Southern Huntingdon (Dist 6 AA 2-1-0) 28 Juniata Valley (Dist 6 A 1-2-0) 14 |
| State College (Dist 6 AAAAAA 3-0-0) 45 Hollidaysburg (Dist 6 AAAAA 0-3-0) 3 |
| Tyrone (Dist 6 AAA 3-0-0) 49 Philipsburg-Osceola (Dist 6 AA 1-2-0) 0 |
| West Shamokin (Dist 6 AA 2-1-0) 14 United (Dist 6 AA 0-3-0) 12 |
District 4 – September 9, 2022
| Athens (Dist 4 AAA 2-1-0) 55 Wyalusing (Dist 4 AA 1-2-0) 7 |
| Bloomsburg (Dist 4 AA 2-1-0) 18 Hughesville (Dist 4 AA 1-2-0) 14 |
| Canton (Dist 4 A 3-0-0) 35 Wellsboro (Dist 4 AA 0-3-0) 0 |
| Danville (Dist 4 AAA 3-0-0) 69 Central Columbia (Dist 4 AA 1-2-0) 0 |
| Jersey Shore (Dist 4 AAAA 3-0-0) 63 Selinsgrove (Dist 4 AAAA 2-1-0) 0 |
| Loyalsock (Dist 4 AAA 3-0-0) 27 Southern Columbia (Dist 4 AA 2-1-0) 10 |
| Mifflinburg (Dist 4 AAAA 3-0-0) 35 Shamokin (Dist 4 AAAA 1-2-0) 21 |
| Milton (Dist 4 AAA 3-0-0) 42 Midd-West (Dist 4 AAA 1-2-0) 0 |
| Montgomery (Dist 4 A 1-2-0) 36 Cowanesque Valley (Dist 4 AAA 0-3-0) 20 |
| Montoursville (Dist 4 AAA 2-1-0) 24 Lewisburg (Dist 4 AAAA 0-3-0) 21 |
| Mount Carmel (Dist 4 AA 3-0-0) 55 Warrior Run (Dist 4 AA 0-3-0) 7 |
| Shikellamy (Dist 4 AAAA 1-2-0) 23 Central Mountain (Dist 6 AAAAA 0-3-0) 3 |
| South Williamsport (Dist 4 AA 2-1-0) 72 Columbia Montour VT (Dist 4 AAAA 1-2-0) 6 |
| Troy (Dist 4 AA 3-0-0) 56 North Penn-Mansfield (Dist 4 AAA 0-3-0) 14 |
District 5 – September 9, 2022
| Bedford (Dist 5 AAA 3-0-0) 51 Westmont Hilltop (Dist 6 AA 1-2-0) 7 |
| Berlin Brothersvalley (Dist 5 AA 3-0-0) 49 Meyersdale (Dist 5 A 0-2-0) 0 |
| Chestnut Ridge (Dist 5 AA 3-0-0) 42 Forest Hills (Dist 6 AA 0-3-0) 19 |
| Conemaugh Township (Dist 5 A 3-0-0) 28 Claysburg-Kimmel (Dist 6 A 1-2-0) 0 |
| Northern Bedford (Dist 5 A 3-0-0) 41 Everett (Dist 5 AA 0-3-0) 0 |
| North Star (Dist 5 AA 1-2-0) 39 West Branch (Dist 6 A 1-2-0) 20 |
| Windber (Dist 5 AA 3-0-0) 56 Conemaugh Valley (Dist 6 A 0-3-0) 7 |
District 8 & 9 – September 9, 2022
| Westinghouse (Dist 8 AA 3-0-0) 59 Perry (Dist 8 AA 1-2-0) 6 |
| Brockway (Dist 9 AA 2-1-0) 70 Coudersport (Dist 9 A 1-2-0) 16 |
| Central Clarion (Dist 9 AA 3-0-0) 43 Union_AC Valley (Dist 9 A 1-2-0) 6 |
| Clearfield (Dist 9 AAA 2-1-0) 41 DuBois (Dist 9 AAAA 2-1-0) 7 |
| Elk County Catholic (Dist 9 A 3-0-0) 30 Bucktail (Dist 4 A 1-1-0) 16 |
| Karns City (Dist 9 AA 1-2-0) 28 Ridgway (Dist 9 AA 0-3-0) 0 |
| Keystone (Dist 9 A 3-0-0) 20 Brookville (Dist 9 AA 0-3-0) 19 |
| Moniteau (Dist 9 AA 1-2-0) 20 Cameron County (Dist 9 A 0-3-0) 12 |
| Otto-Eldred (Dist 9 A 2-1-0) 33 Bradford (Dist 9 AAAA 0-3-0) 26 |
| Port Allegany (Dist 9 A 2-1-0) 28 Smethport (Dist 9 A 1-2-0) 0 |
| Redbank Valley (Dist 9 A 3-0-0) 28 Punxsutawney (Dist 9 AAA 2-1-0) 14 |
| Saint Marys (Dist 9 AAA 3-0-0) 30 Kane (Dist 9 AA 0-3-0) 0 |
District 6 – September 10, 2022
District 5 – September 10, 2022
District 9 – September 10, 2022