November 10, 2022
District 6
| Bishop Guilfoyle (Dist 6 AA 9-3-0) 32 Richland (Dist 6 AA 11-1-0) 22 |
| Juniata (Dist 6 AAAA 8-3-0) 17 DuBois (Dist 9 AAAA 5-6-0) 7 |
| Penns Valley (Dist 6 AA 10-2-0) 34 Bald Eagle Area (Dist 6 AA 8-4-0) 14 |
| State College (Dist 6 AAAAAA 11-0-0) 28 Altoona (Dist 6 AAAAAA 6-6-0) 7 |
Other Districts
| Perkiomen Valley (Dist 1 AAAAAA 11-1-0) 27 Souderton (Dist 1 AAAAAA 9-3-0) 14 |
| Delaware Valley (Dist 2 AAAAAA 7-5-0) 24 Scranton (Dist 2 AAAAAA 8-4-0) 21 |
| Lackawanna Trail (Dist 2 AA 8-4-0) 40 Jenkintown (Dist 1 A 6-5-0) 7 |
| Lakeland (Dist 2 AAA 12-0-0) 20 Dunmore (Dist 2 AA 8-4-0) 14 |
| Jersey Shore (Dist 4 AAAA 12-0-0) 35 Selinsgrove (Dist 4 AAAA 9-3-0) 7 |
| Windber (Dist 5 AA 11-1-0) 14 Northern Bedford (Dist 5 A 11-1-0) 0 |
| Westinghouse (Dist 8 AA 11-0-0) 59 Berlin Brothersvalley (Dist 5 AA 11-1-0) 7 |
| Bethlehem Freedom (Dist 11 AAAAAA 10-2-0) 28 Emmaus (Dist 11 AAAAAA 10-2-0) 27 |
| Northern Lehigh (Dist 11 AA 11-1-0) 40 Tri-Valley (Dist 11 A 10-2-0) 15 |
| North Schuylkill (Dist 11 AAA 10-2-0) 51 Palmerton (Dist 11 AA 7-5-0) 21 |
| Northwestern Lehigh (Dist 11 AAAA 10-2-0) 35 Notre Dame (Dist 14 AAA 9-3-0) 34 |
| Parkland (Dist 11 AAAAAA 8-4-0) 31 Northampton (Dist 11 AAAAAA 11-1-0) 13 |
| St. Joseph’s Prep (Dist 12 AAAAAA 8-1-0) 21 La Salle College (Dist 12 AAAAAA 5-6-0) 13 |
November 11, 2022
| Clearfield (Dist 9 AAA 8-3-0) 13 Saint Marys (Dist 9 AAA 7-5-0) 7 |
| Grove City (Dist 10 AAA 8-3-0) 22 Sharon (Dist 10 AAA 6-5-0) 21 |
| McDowell (Dist 10 AAAAAA 10-2-0) 42 Allderdice (Dist 8 AAAAAA 4-7-0) 15 |
| Slippery Rock (Dist 10 AAA 7-4-0) 28 Hickory (Dist 10 AAA 5-6-0) 0 |
November 12, 2022
| Canton (Dist 4 A 11-1-0) 42 Muncy (Dist 4 A 10-1-0) 7 |
| Danville (Dist 4 AAA 11-0-0) 49 Athens (Dist 4 AAA 7-5-0) 0 |
| Loyalsock (Dist 4 AAA 11-1-0) 69 Mifflinburg (Dist 4 AAAA 9-3-0) 42 |
| Mount Carmel (Dist 4 AA 12-0-0) 48 Hughesville (Dist 4 AA 5-7-0) 13 |
| Southern Columbia (Dist 4 AA 9-3-0) 48 Troy (Dist 4 AA 9-3-0) 12 |
| Central (Martinsburg) (Dist 6 AAA 10-2-0) 35 Penn Cambria (Dist 6 AAA 9-2-0) 6 |
| Northern Cambria (Dist 6 A 9-3-0) 41 Cambria Heights (Dist 6 A 8-4-0) 0 |
| Penns Manor (Dist 6 A 11-1-0) 21 Portage (Dist 6 A 7-5-0) 7 |
| Brockway (Dist 9 A 8-4-0) 7 Redbank Valley (Dist 9 A 9-2-0) 3 |
| Central Clarion (Dist 9 AA 10-1-0) 35 Brookville (Dist 9 AA 6-6-0) 0 |
| Port Allegany (Dist 9 A 10-1-0) 18 Keystone (Dist 9 A 7-5-0) 6 |